THE EBNA3 FAMILY OF EPSTEIN-BARR VIRUS NUCLEAR PROTEINS ASSOCIATES WITH THE USP46/USP12 DEUBIQUITINATION COMPLEXES TO REGULATE LYMPHOBLASTOID CELL LINE GROWTH.

The Epstein-Barr virus (EBV) nuclear proteins EBNA3A, EBNA3B, Heel Sleeve and EBNA3C interact with the cell DNA binding protein RBPJ and regulate cell and viral genes.Repression of the CDKN2A tumor suppressor gene products p16(INK4A) and p14(ARF) by EBNA3A and EBNA3C is critical for EBV mediated transformation of resting B lymphocytes into immortal

The probability distributions of field Wigs differences ∆x(τ)=x(t+τ)-x(t), where the variable x(t) may denote any solar wind scalar field or vector field component at time t, have been calculated from time series of Helios data obtained in 1976 at heliocentric distances near 0.3 AU.It is found that for comparatively long time l

This study aimed to explore the beliefs and attitudes of a group of senior veterinary students regarding One Health and to evaluate their levels of confidence in advising the general public on preventative health issues at the human−animal interface.An online survey was communicated to senior veterinary students who were in their last two yea

Purpose: Target therapy against molecular markers of EGFR family has been recently used in the treatment protocol of several diseases.However, the role of Her-2/neu in OSCC is a matter of controversy and more studies are required to clarify the role of Her-2/neu in OSCC.We aimed Jeans to investigate the role of Her-2/neu in the process of carcinoge